Spravato Treatment


In early 2019, the FDA approved Spravato™, an esketamine nasal spray designed to relieve treatment-resistant depression. TMS & Brain Health, in Santa Monica, California, offers Spravato treatment to help you alleviate your depression symptoms and restore your quality of life. If you’re struggling with treatment-resistant depression, call TMS & Brain Health or request an appointment online today to find out how Spravato can help you.

What is spravato?

Spravato is an esketamine nasal spray that can alleviate the symptoms of treatment-resistant depression. Ketamine is a chemical which consists of two mirror-image molecules, S-ketamine and R-ketamine. When used as an anesthetic or in an intravenous infusion, both the S and R molecules are included. However, Spravato only uses the S molecule.

What conditions improve with Spravato?

Spravato is FDA-approved for treatment-resistant depression. In almost all cases, Spravato is prescribed for patients who have tried other types of medication and therapy without success. Because it is FDA-approved, some insurance companies may cover Spravato.

What should I expect while using Spravato?

TMS & Brain Health offers Spravato as an in-office treatment. However, before starting any treatment, we conduct a comprehensive evaluation to ensure that this is the best possible option for you. Spravato will be prescribed in one of two dosages: 56 mg, or 84 mg. We assist in the administration of the nasal spray.

Esketamine can trigger some initial and short-lived side effects such as dizziness, floating sensations, or mild hallucinations. You rest comfortably at TMS & Brain Health under the supervision of a member of the clinical team for approximately two hours. When your provider releases you, you will need a friend or family member to drive you home. You may be tired for the rest of the day, but any fatigue will pass by the time you wake up the next morning.

Your provider at TMS & Brain Health creates a customized treatment plan to address your specific needs. Most patients begin with two Spravato treatments a week for the first month, followed by once a week treatments in the second month. After the second month of treatment, patients typically have a Spravato treatment once a week or once every two weeks, depending on their needs. The first treatment is always 56 mg.

Am I a good candidate for Spravato?

Spravato might be a good treatment option for you if conventional treatments for depression haven’t relieved your symptoms, and you are in good physical health. If you have a history of substance abuse, your provider may recommend an alternative such as Transcranial Magnetic Stimulation (TMS).

Find out if our treatment programs are right for you

Let us help you today!

TMS & Brain Health is not a healthcare provider and does not render any psychiatry or other medical services, including but not limited to TMS, Ketamine, or Neurofeedback. IOP services are rendered through a separate, affiliated entity. Rather, TMS & Brain Health performs administrative services for various psychiatrists and/or psychiatry and/or medical practices.  Further, this website does not provide medical advice, diagnosis, or treatment. More information can be found at our disclaimer page.